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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00d4d6b84eb0bbc380aa802da3437fbfb5fa80cba98d12a50ea1157f0fa47d7' 
  AND token = 'wmvT4HeoV5Hh/WC8BMhAQDc8w3FB+j5PQRSrXbfT2KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}