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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c241a89189acf88e08c7d94b69a87f4572013a6253f69abec9f34917c99d842f' 
  AND token = 'HU7s0yArQkbLI0ClYmoa2xIDYLwus3e7ofzoIcwOzgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}