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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05bac4b0ac51823a0e5ee6426332ddb18458fbfbb1c9d61475ce9799f8f620f0' 
  AND token = 'uzZ5H5p+AEc6DkhYhnLPQ2GPf/xAZ0R+lbohekmV1cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}