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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65117fee534b91bbc079693d7baa815c3b0fa8129874e9f9e28b51072dcd4b1' 
  AND token = 'pukWrrWmjDmNEx18GUKFRzBES6N69Bl2s6zSeG+XVZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}