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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21439360ec940f5147fbc8f7aae028bd5619a18f1b3cac8a77cfb14147dbd0ed' 
  AND token = '7c8y5b9pnLJdVImr/7PPiI4ti+ENZ2OgxOgLr7T9tks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}