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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19bda8c8bd72424474b4467bc42df84257407b23f44cc6bdd51e9bbbc25940a5' 
  AND token = '9GC090X6DBaiManJhy2f2y+Gxr+rrulvrXdJZDs4Ygk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}