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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7645144c78ec7ff318b2bbd9c42ea5c4125898776a9314fa74199be6244e1a14' 
  AND token = 'nFc2kWlXf6KnwaYobsaj/Q+bnw83dFrXZW+4IOLY1go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}