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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbdf572077cffcc87bb3695d43e11adb3b28199a9e6763def9b3d85396f0b50' 
  AND token = '4C5XsHOeLIt+koXeamBO6KqdZEYy5meloS2pucyVggw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}