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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073b2ac45f61e208c78b186af95c3c67f151943f67bc9e206bd313465c6e9b00' 
  AND token = 'dzW9wLiOaS2HI5TqiW6TZm3RK9o9AUCUCcJWsXpBHGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}