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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79a40ac837f00756c32ea1594e553649ce5df98df4a36b00931385278563ce7b' 
  AND token = 'CtA1125/48tb1HsrFbTVy/im19TnwGMQYWjHaDTx5QY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}