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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc4db5e4ee7106f20b0c4157e580ae165a13e9ed92cd9c5958bb16edc10a403' 
  AND token = 'IODjAc+dYAeE89kNGSJ+NbBnxmp+bBQBBdrAh4FMRpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}