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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0068890f9561db6818a1e7ac905f3421d9612f953538518818cc5c19477a79' 
  AND token = 'vvXdxmGtYR7VC0xgWKW+iMqTX6NiKTS6gWMTkwyF8F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}