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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b487704dd01e8e2fe5369c0b62fad24de45bfdc3b811e4e39a8f28a4514785' 
  AND token = '9IcF3Yv4fO6DtkHWXHeN2TjulFGIVs3dGmTkc8MjKKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}