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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2681c3ef71ee70c8a7d8a660bbb64a56d507895064f9c10216b8bd11dea1e6d0' 
  AND token = 'cRFDuolO+KRWuJ1aMi2LBNFoxtLSeQoK4PyppatNklQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}