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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99d8340474f175ead1d40fdb798e04904449b7a72ad0a043825a1a00648d2ef' 
  AND token = 'eM7e00v4WyUCBLkSxTBGQYuqR1ud0tIrjQ+GzhyE2Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}