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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7093736dbe56faad376a09dba0ac1059fa684fc226016a4ade5f8d4b102327' 
  AND token = 'ms9VUmaQ16CZcCFpnkVrk0Qw3hXaRW0iQwEReP+Q9H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}