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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366d35a6df7532957a59e4b60e437dab6038e6b7434f72437c8a25357ed0c3e2' 
  AND token = 'IQR/KLuealVmoMTq4OWkz16j9K3G/uR3wJy15cN+Uyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}