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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80816f9ffeaf301aefa45aa68698c1129ba3d5c968bb84947df0502b3641f7e6' 
  AND token = 'h2VJ47AiPMpEXnLE4xXc+A3cSg945HfpXB/oGpWvoAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}