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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ff986c3fefe4d622475a7f5957fc8b768fd1b7a89856dfded37b6d96ca4633' 
  AND token = 'gufq6msWiAE0NyerzMz+M4fxLqbNirATCyCkAqMYucI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}