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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '508c8e94ccd8d8591d3a9e29bec404a31071358911dc6754cdec931b0458625d' 
  AND token = 'eMT/8Mqoe6MuVtib6K0bSL3KwFXtbGo4clZaNRyGk1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}