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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '670c00e57d14764d75ccd48f0aeed89f5d0133a3081f893f75a76f84ae806e24' 
  AND token = 'zsi/J1AeyvdUD1ULSZ6pfr4Z6LhK4pDOu9jVDeinszU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}