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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '296a970070ee480791d2cf77d239ac6807550218a80d9c5f87e88780965bef45' 
  AND token = 'dSd0h24UJYJxaXT20JPx8sEVHzqPOoD6vDUmqbeyrLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}