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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b798b11b0a749ad06fa9507b2b08416156a361b5e7a39f174a76037cec40008' 
  AND token = '1D/e/lTRPmhd84ek1CPIXTbCXpgbjkGEl1VdjikSfg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}