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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1ddd1e56b7f72eab2b7779a8ca710fc2e38b537d87ed49152e236e8866d0e0' 
  AND token = 'GjpQae+PxgY7OiFHn0IfSC961KSsNjFQEhIPJ9DWVYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}