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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e9e5acd18981ed65da035e5f372c91c3eef7fe1beeee9c284483227fe63e50d' 
  AND token = 'AMUvMyAmedpq2/a+tAqO7fh3agoKe9LCJqcpOZL5uAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}