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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b8c89b44f20b8bb6890a078ba760fb5e5c0e402e77e60e0a90daafa7bbac501' 
  AND token = 'A3wAdfNadMYp76jJCwp1/rVyPpldL+9zwG+D7cPiE5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}