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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48396588c0879dca5a36a3f34164546b82a7fe74aa9213b4b14de57ae8b54f44' 
  AND token = '5lmb5M7lPCW35fhyCLOcT0OLi/ivjA6yT57VkcZCCZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}