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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a92f68bdaaa03adc47defd6275ac58151070e9a40dd23674c2d2fa3179f4c0' 
  AND token = 'iAxtPNpn3Ov8xpoWoWtQs4sy3C50gnSCsqk4Y+CEcH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}