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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50eeff41117cff36a66c1bb36a80d37e5f9edf3290a920b6ae8cae7fd0e04be8' 
  AND token = 'dirAgPgwBt/ATwvwLF61R3ThIrkzvdwn9SwA0vrqv+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}