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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8afb6e53dc6e3b392842e6474c58c9745367d85f8eb51bd5f378d2eaf94f50' 
  AND token = 'Bt67yTyMGVR7bT97nNrYVtddPZdy5vZOw182hAQBMXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}