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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26253e4f49c6cbc8f2505c5e922221fdfe0a8dc3f77e398a4bb6056bbe2d4d15' 
  AND token = 'b1Xii80qG1IBR7oHHvRG/P5t6+cUzQfIDjZivgOiNe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}