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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b96cb9f8ce29a89a3a99b670408092c408e5e5c4fadfb9e2a5320b7246b9a3' 
  AND token = 'k2JSlYW0BAh4M7/dmd1tW71f0K2DiKmeu+aRqipCodI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}