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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ede2ea70f0e245813d826f7054ebe24a124cf69d43816b9c3ae4b7c6de651ac' 
  AND token = '+KkSV+8dbUZ6NjZkZa/DS240Hyp3VxfVwaKp3905p7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}