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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b6308eee950fb07527cea4d7358780c3216dcfb8d0a8e12f10729e8e04b873' 
  AND token = 'ioO/ZbLyMBN5vLRX6D+RGnEdnQhl9QRGR/mnnqFChC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}