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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ca4da634093b17162a96921e0b49d98c213a028da6bb5495affd78b6f91245' 
  AND token = 's0x+zlcFxiZbwAy/B6MavoHk36mZARpIygabut7lxCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}