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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec0e1dc3e337170362bf7881f10c0cb389297657dc91ef1c577c326b592801b' 
  AND token = '2H28p9hr5JYwyyJCN2c/pGBSEXfnHoB4Juf6PqMg/eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}