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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d13bc99683c64edd09fbf12935863de9dad3600c65c14dbc2f33a28c2a7807c' 
  AND token = 'eM1naW1JhzLcrapLM9mVKsQn2mYJQEkXXL98Cmyz9Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}