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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '263cf97f078a124c07ca2ee3ec36ec74f3a086e20606bf73e496925a9653c812' 
  AND token = 'EMobmrUSOZfXfQA+yN9+6+HxV6EWWt0GQ2H8QCuglM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}