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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ccdf5149f26871bcf996c0179c2686649cd7afa8de5bf702b6ce027e64be564' 
  AND token = '8dP5SVhcKmbXiqe8/U+JCEwgch57+KiC/UqtJcAtndE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}