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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90fd23facc0805a6278e4615583cb3e9209b70c2317b8fb96540357a37edb9a4' 
  AND token = 'jFHQlbRVeu8mqz58I6mpVwn2y8ALKRubqTP0LUeJisE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}