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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fdb3b4ff31bd5400147f4b2fe660d969ea48bf8d52389ef19b117f5d22d91a' 
  AND token = 'jTwDFS8YYgsFo5l9ipY4WwMPTBPRw76ZAwFNYyzCDDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}