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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2623921abe95534dd087cbed8b80b114c93b6234b42219b5491b133395f2cb2e' 
  AND token = 'IMDZmAjGk2NreT8H+7M+Gz++Bbjr32n8Hgn1mF/R7Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}