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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aad145b14104a23264a5d550b023582e6033fed00b171c8c306afc24c13ada' 
  AND token = '7Dx/C3Bvmv0pA57Yo2QOA9aoBwa7jf7qLzgAC21u/Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}