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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9709ce96209a1a90e3d1e059221b3e3fbf4ad645fc2e30634b104f0b60c9102' 
  AND token = 'MN7WQ7GhjK+CxmlnXlKxVf8JWsnhDbBZAoUtisn0oow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}