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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7b5fbb15c1f6f0112873c3707ff1612c12b50e3b9499526d625c6b8c88c834' 
  AND token = 'EdC3eenvEkQKHzU/y8nQXuclyzI3EW0VT27lzKXZzXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}