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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8941ad6c5961e91a330bd08cb6e47e6d45f32f5c1dd5d8d5e204e79d795083f' 
  AND token = '+Wf1XX2+uP7iHo6uvN7U2jptAFFol1Nik2ytw9Z7FyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}