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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def5cba4e3a7772d8baa3cbebeac4fa0e82f0875a16629a948b7b448f9b461dc' 
  AND token = 'uzf2OzslAG8NDw2Uz4xb2KRy3ahBLA1MRWpCE9nBqZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}