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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a80f9672bbb474adb0167bb870bbc5278615928ba3d2e4e12b91a4ea5c2bb4' 
  AND token = 'GNxjQT3wnQqtQrOgh5In5ZlmzLGYsA04HWXO8f6ySg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}