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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b34a2db6cf50dc8c0a93081ae7de3e6272c15954b28e741796360d7bc627c04' 
  AND token = 'pE9cF+hl96c6s2Zz9naxghPDMTEsxqXRfXu8VsKUa7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}