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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2072b6a960ba4e438c9ef07838609ed16101b2ed1aa1f4f9790bb0606b3fb928' 
  AND token = 'nqpooeWXCbEHF15NK23kGt/vYkacq7wJaGw2eH7z1QQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}